Systemic miRNA-7 delivery inhibits tumor angiogenesis and growth in murine xenograft glioblastoma
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چکیده
منابع مشابه
Systemic miRNA-7 delivery inhibits tumor angiogenesis and growth in murine xenograft glioblastoma
Tumor-angiogenesis is the multi-factorial process of sprouting of endothelial cells (EC) into micro-vessels to provide tumor cells with nutrients and oxygen. To explore miRNAs as therapeutic angiogenesis-inhibitors, we performed a functional screen to identify miRNAs that are able to decrease EC viability. We identified miRNA-7 (miR-7) as a potent negative regulator of angiogenesis. Introductio...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2014
ISSN: 1949-2553
DOI: 10.18632/oncotarget.2235